Aldolase-Distinctive Characters in Archaeal Enzymes
نویسندگان
چکیده
منابع مشابه
Archaeal Enzymes and Applications in Industrial Biocatalysts
Archaeal enzymes are playing an important role in industrial biotechnology. Many representatives of organisms living in "extreme" conditions, the so-called Extremophiles, belong to the archaeal kingdom of life. This paper will review studies carried by the Exeter group and others regarding archaeal enzymes that have important applications in commercial biocatalysis. Some of these biocatalysts a...
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Thermophilic enzymes have advantages for their use in commercial applications and particularly for the production of chiral compounds to produce optically pure pharmaceuticals. They can be used as biocatalysts in the application of 'green chemistry'. The thermophilic archaea contain enzymes that have already been used in commercial applications such as the L-aminoacylase from Thermococcus litor...
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for the enzyme in vivo unless an alkaline micro-environment was postulated or conditions were present in vivo which could potentiate inhibition by UMP at near-neutral pH (Yon, 19726). Substances such as deoxycholate which can bind to the hydrophobic site on the enzyme may provide such potentiation. Fig. 2 shows the effects of UMP and deoxycholate at pH values between 7 and 11. In the absence of...
متن کاملStructure, function and evolution of the Archaeal class I fructose-1,6-bisphosphate aldolase.
FBPA (fructose-1,6-bisphosphate aldolase) catalyses the reversible aldol condensation of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate to form fructose 1,6-bisphosphate. Two classes of FBPA, which rely on different reaction mechanisms, have so far been discovered, class I mainly found in Eucarya and class II mainly in Bacteria. Only recently were genes encoding proteins with FBPA ac...
متن کامل[Aldolase].
OH OH Two main classes of aldolases are found in Nature. Type I aldolases activate the nucleophilic partner by forming an imine as an intermediate; this type of enzyme is found in animals and higher plants. Type II aldolases occur in microorganisms and they require R 2 to be a hydroxy group. These enzymes feature a Zn 2+ ion that promotes the reaction by forming a chelate with both the carbonyl...
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ژورنال
عنوان ژورنال: Trends in Glycoscience and Glycotechnology
سال: 2013
ISSN: 0915-7352,1883-2113
DOI: 10.4052/tigg.25.71